You can verify that some fold achieves some energy state. What you cannot effici... | Hacker News

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		tromp on Feb 23, 2021 \| parent \| context \| favorite \| on: Gridcoin: An open-source cryptocurrency that rewar... You can verify that some fold achieves some energy state. What you cannot efficiently verify is that it's the best possible fold, achieving the global minimum energy.

woadwarrior01 on Feb 23, 2021 [–]

> You can verify that some fold achieves some energy state.

IMO, that makes it similar to Difficulty[1] (and the related target) in Bitcoin's POW scheme.

[1]: https://en.bitcoin.it/wiki/Difficulty

tromp on Feb 23, 2021 | [–]

except that with difficulty, you know the expected effort needed to pass the threshold. with folding of arbitrary proteins, you have no idea.

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